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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK14
All Species:
22.12
Human Site:
T105
Identified Species:
37.44
UniProt:
O94921
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94921
NP_036527.1
469
53057
T105
N
A
C
I
N
F
K
T
S
S
T
G
K
E
S
Chimpanzee
Pan troglodytes
XP_519189
469
53035
T105
N
A
C
I
N
F
K
T
S
S
T
G
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001102520
469
53072
T105
N
A
C
I
N
F
K
T
S
S
T
G
K
E
S
Dog
Lupus familis
XP_532455
469
53036
S105
N
A
C
I
N
F
K
S
S
S
T
G
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O35495
469
52977
S105
N
A
C
I
N
F
K
S
S
S
A
G
K
E
S
Rat
Rattus norvegicus
O35831
523
59414
Q162
D
G
Y
L
E
K
L
Q
I
S
S
P
P
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516045
337
37621
I18
S
L
A
R
P
V
P
I
A
D
I
C
S
R
S
Chicken
Gallus gallus
XP_418647
773
84016
T409
N
A
C
I
N
F
K
T
S
S
A
G
K
E
S
Frog
Xenopus laevis
Q6DJM7
435
49211
P90
F
E
K
T
S
N
Q
P
T
S
P
K
F
G
K
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
E92
L
N
L
E
K
L
G
E
G
T
Y
A
T
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523904
522
59750
E175
K
P
P
R
P
K
S
E
V
F
L
N
K
Q
E
Honey Bee
Apis mellifera
XP_624994
494
56118
E135
R
P
P
R
P
K
S
E
V
F
L
G
P
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
Baker's Yeast
Sacchar. cerevisiae
P17157
305
34888
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.7
99.1
N.A.
98.5
43
N.A.
60.7
58.5
85.2
51.5
N.A.
48.4
50
N.A.
N.A.
Protein Similarity:
100
99.5
99.7
100
N.A.
99.3
59
N.A.
63.3
59.5
89.3
63.1
N.A.
61.2
63.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
6.6
93.3
6.6
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
20
93.3
26.6
6.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
8
0
0
0
0
0
8
0
15
8
0
0
0
% A
% Cys:
0
0
43
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% D
% Glu:
0
8
0
8
8
0
0
22
0
0
0
0
0
43
8
% E
% Phe:
8
0
0
0
0
43
0
0
0
15
0
0
8
8
0
% F
% Gly:
0
8
0
0
0
0
8
0
8
0
0
50
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
43
0
0
0
8
8
0
8
0
0
0
0
% I
% Lys:
8
0
8
0
8
22
43
0
0
0
0
8
50
0
8
% K
% Leu:
8
8
8
8
0
8
8
0
0
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
43
8
0
0
43
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
15
15
0
22
0
8
8
0
0
8
8
15
0
8
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
22
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
8
0
15
15
43
58
8
0
8
0
50
% S
% Thr:
0
0
0
8
0
0
0
29
8
8
29
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
15
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _